Neurons send messages in an electrochemical manner – chemicals or ions bring about an electrical impulse. Both neurons as well as muscle cells have the property to be electrically excitable, so they can send electrical nerve impulses which are brought about because of certain events in the cell membrane.

The nervous system primarily works by carrying out an electrical impulse or a signal through the length of a nerve and sends it across the synaptic cleft to a muscle fibre or to another nerve. As soon as a nerve impulse gets to the terminus of a nerve, a flood of ions endorses the discharge of vesicles that have neurotransmitters (like acetylcholine), which then allows this messenger molecule to spread throughout the synaptic cleft and attach to specific receptors.